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PDE11A Antibody - C-terminal region : HRP (ARP64064_P050-HRP)

Selected Variant

ARP64064_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Phosphodiesterase 11A

Gene Aliases

PPNAD2

Gene ID

50940

Swiss Prot

Q9HCR9-4

Accession Number

NP_001070664

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Target

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

Shipping Conditions

Wet Ice

Protein Length

489

NCBI Gene Symbol

PDE11A

NCBI GB Accession Number

PDE11A

Host or Source

Rabbit

Protein Name

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Nucleotide Accession Number

NM_001077196

Peptide Sequence

VTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQA

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