ARL13B Mouse Monoclonal Antibody [A4E4]
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
ADP-ribosylation factor-like protein 13B ADP-ribosylation factor-like protein 2-like 1 ARL2-like protein 1
Swiss Prot
Q3SXY8 Human
Cellular Locus
Cell membrane, Cell projection, Cilium, Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within human ARL13B aa 370-428.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB
Positive Control
293T cell lysate, HL-60 cell lysate.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 49 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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