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Purified Anti-Human CD38 Antibody[HB-7]

Product Specifications

Background

CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD (P) + into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose . CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

Abbreviation

CD38

Gene ID

952

UniProt

P28907

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD38 protein

Target

CADPr hydrolase; ADP-ribosyl cyclase; cyclic ADP-ribose hydrolase; Acute lymphoblastic leukemia cells antigen CD; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38; ADPRC 1; ADPRC1; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; ADP-ribosyl; T10; cyclase;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1) ; Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1) ; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; ADP ribosyl cyclase 1; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; CD 38; CD38 antigen (p45) ; Cd38-rs1; Cyclic ADP ribose hydrolase 1; Ecto nicotinamide adenine dinucleotide glycohydrolase; I19 (mouse) ; Lymphocyte differentiation antigen CD38; NAD (+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse) ; OTTHUMP00000158633; OTTHUMP00000217743

Clonality

Monoclonal

Clone

HB-7

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Stem Cells; Cancer; Metabolism

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG1, κ

Available Sizes

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