Dot1L-IN-8
Dot1L-IN-8 (Compound 15) is a potent and selective Dot1L inhibitor, demonstrating anti-proliferative activity against various leukemia cell lines including HL-60, K562, and MV4-11 with IC50 values ranging from 0.45 to 1.66 μM. This small molecule is a valuable chemical probe for epigenetic research, particularly in studying the role of H3K79 methylation in hematological malignancies in vitro.
Product Specifications
Field of Research
Epigenetics & Chromatin
Molecular Formula
C41H53N7O3S
Molecular Weight
723.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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