EGFR-IN-78

EGFR-IN-78 (A5) is a reversible, cell-permeable inhibitor targeting the EGFR C797S mutant kinase. It demonstrates anti-proliferative activity by suppressing EGFR autophosphorylation, inducing apoptosis, and causing G2/M phase arrest in cellular assays, supporting its investigation in resistant non-small cell lung cancer models.