USP8-IN-2
USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].
Product Specifications
CAS Number
[2477651-11-7]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp8-in-2.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F
Molecular Formula
C19H20ClF3N4OS
Molecular Weight
444.90
References & Citations
[1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP8
Available Sizes
Curated Selection
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