USP8-IN-2

USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].

Product Specifications

CAS Number

[2477651-11-7]

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/usp8-in-2.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F

Molecular Formula

C19H20ClF3N4OS

Molecular Weight

444.90

References & Citations

[1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

USP8

Available Sizes

Curated Selection

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