USP8-IN-2
USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].
Product Specifications
CAS Number
[2477651-11-7]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp8-in-2.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F
Molecular Formula
C19H20ClF3N4OS
Molecular Weight
444.90
References & Citations
[1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal Hepatitis G Virus Antibody [FITC]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
![Rat Monoclonal CD47 Antibody (974222) [Allophycocyanin/Cy7]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)