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MS2177

MS2177 is a potent and selective SETD8 inhibitor with a reported IC50 of 1.9 μM and a KD of 1.3 μM. This compound is a valuable chemical probe for studying H4K20 monomethylation in epigenetic research, applicable in both cell-based and biochemical assays to investigate gene regulation and cellular processes.

Product Specifications

Smiles

COC1=C (OCCN) C=C (N=C (N2CCCC2) N=C3NCCCCCN4CCCC4) C3=C1

Molecular Formula

C24H38N6O2

Molecular Weight

442.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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