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Type II TRK inhibitor 1

Type II TRK Inhibitor 1 is a potent small molecule targeting both wild-type and fusion variants of TRK kinases. It exhibits strong antiproliferative activity in cellular models, such as Ba/F3 cells harboring TRKA G667C or TRKC G696C mutations. This inhibitor is a valuable tool for investigating TRK-driven oncogenesis in both in vitro and in vivo cancer research contexts.

Product Specifications

CAS Number

2937543-72-9

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C35H33F3N8O3

Molecular Weight

670.68

Storage Conditions

-20°C

Notes

For research use only.

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