SB-T-1214
Product Specifications
Target
C-Myc|||Apoptosis|||OCT
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis|||Membrane transporter/Ion channel
Bioactivity
SB-T-1214 (SBT) is a taxane-based drug known for its ability to effectively suppress the expression of stem cell-related genes (Oct4, Sox2, and c-Myc) and induce apoptosis in drug-resistant tumorigenic CD133+/CD44+ colon cancer spheroids. In Pgp+ DLD-1 human colon tumor xenograft mouse models, SB-T-1214 successfully inhibits tumor growth. This compound is relevant for anti-tumor research, particularly against drug-resistant tumors such as colon, pancreatic, and renal cancers.
Smiles
O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(=O)C6CC6)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(OC(C)(C)C)=O)C=C(C)C)O)=O)C5)[H]
Molecular Formula
C45H59NO15
Molecular Weight
853.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881159057817606/T210736
CAS Number
178250-23-2
Available Sizes
Curated Selection
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