What is the catalog number for SB-T-1214?

The catalog number for SB-T-1214 is T210736.

What sizes are available for SB-T-1214?

SB-T-1214 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does SB-T-1214 come in?

SB-T-1214 is available in 2 different pack sizes.

Is SB-T-1214 in stock?

SB-T-1214 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SB-T-1214?

SB-T-1214 is manufactured by Molfinity.

What is the estimated delivery time for SB-T-1214?

Estimated delivery time for SB-T-1214 is approximately 10 business day(s), depending on your location.

SB-T-1214

Product Specifications

CAS Number

178250-23-2

Target

C-Myc, Apoptosis, OCT

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Membrane transporter/Ion channel

Bioactivity

SB-T-1214 (SBT) is a taxane-based drug known for its ability to effectively suppress the expression of stem cell-related genes (Oct4, Sox2, and c-Myc) and induce apoptosis in drug-resistant tumorigenic CD133+/CD44+ colon cancer spheroids. In Pgp+ DLD-1 human colon tumor xenograft mouse models, SB-T-1214 successfully inhibits tumor growth. This compound is relevant for anti-tumor research, particularly against drug-resistant tumors such as colon, pancreatic, and renal cancers.

Smiles

O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(=O)C6CC6)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(OC(C)(C)C)=O)C=C(C)C)O)=O)C5)[H]