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EDP-305

EDP-305 is a potent and selective oral FXR agonist, demonstrating EC50 values of 34 nM and 8 nM in different cellular assays. It shows consistent antifibrotic activity in research models for liver diseases, including primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH), as supported by in vitro and in vivo studies.

Product Specifications

CAS Number

1933507-63-1

Field of Research

Metabolism Research

Purity

97.17% (May vary between batches)

Smiles

O[C@H]1[C@@]2 ([C@@] ([C@]3 (C) [C@] ([C@H]1CC) (C[C@H] (O) CC3) [H]) (CC[C@@]4 (C) [C@]2 (CC[C@@]4 ([C@@H] (CCNC (NS (=O) (=O) C5=CC=C (C (C) (C) C) C=C5) =O) C) [H]) [H]) [H]) [H]

Molecular Formula

C36H58N2O5S

Molecular Weight

630.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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