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GSK-J1 lithium salt

GSK-J1 lithium salt is a potent and selective small molecule inhibitor of the H3K27me3/me2 demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 of 60 nM against KDM6B. This inhibitor is widely used in vitro and in vivo to investigate the role of these epigenetic regulators in cancer, immunology, and stem cell biology.

Product Specifications

CAS Number

2309668-29-7

Field of Research

Epigenetics & Chromatin

Smiles

[Li]OC (CCNC1=NC (C2=NC=CC=C2) =NC (N (CC3) CCC4=C3C=CC=C4) =C1) =O

Molecular Formula

C22H22LiN5O2

Molecular Weight

395.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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