CPT-Se4
CPT-Se4 is a selenium-modified camptothecin derivative that potently induces apoptosis in cancer cells by disrupting redox balance, elevating ROS, and depleting glutathione. It demonstrates broad cytotoxicity in vitro against multiple cancer cell lines, including HeLa and Hep G2, with IC50 values in the low micromolar range, supporting its investigation as an antitumor agent.
Product Specifications
CAS Number
2968315-03-7
Field of Research
Cell Biology, Molecular Biology
Smiles
CC[C@@]1 (C2=C (COC1=O) C (=O) N3CC4=CC5=CC=CC=C5N=C4C3=C2) OC (=O) OCC[Se][Se]CCO
Molecular Formula
C25H24N2O7Se2
Molecular Weight
622.39
Storage Conditions
-20°C
Notes
For research use only.
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