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Fazarabine

Fazarabine (Kymarabine) is an orally-active aza-cytidine arabinoside analog. Its active triphosphate form incorporates into DNA to inhibit synthesis, inducing tumor cell death, with efficacy dependent on tumor deoxycytidine kinase levels. It has been investigated in preclinical in vitro and in vivo studies for hematological malignancies and solid tumors.

Product Specifications

CAS Number

65886-71-7

Smiles

O[C@@H]1[C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) N=C (N) N=C2

Molecular Formula

C8H12N4O5

Molecular Weight

244.2

Storage Conditions

-20°C

Notes

For research use only.

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