Jatrorrhizine chloride
Jatrorrhizine chloride is an orally bioavailable inhibitor of the uptake-2 transporter. It demonstrates neuroprotective effects in vitro, such as reducing H2O2-induced apoptosis in HT22 hippocampal neurons by suppressing the MAPK pathway, supporting research in neurodegeneration and oxidative stress models.
Product Specifications
CAS Number
6681-15-8
Product Name Alternative
Cholinesterase (ChE), Cytotoxic, depressive disorder, E. histolytica, Bacterial, antiplasmodial, antioxidant, antimicrobial, antiamoebic, antidepressant-like, antidepressant, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, alkaloid, Alzheimer's disease, 5-HT Receptor, AChE, falciparum, Inhibitor, Jatrorrhizine, Jatrorrhizine chloride, Jatrorrhizine Chloride, inhibit, PMAT, OCT, Neprotine Chloride, Neprotine chloride, neuroprotective, quaternary isoquinoline, Serotonin Receptor, Yatrorhizine chloride, Yatrorhizine Chloride
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.68 mM) ; DMSO:8 mg/mL (21.4 mM)
Smiles
[Cl-].COc1cc-2c (CC[n+]3cc4c (OC) c (OC) ccc4cc-23) cc1O
Molecular Formula
C20H20ClNO4
Molecular Weight
373.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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