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(R) -MLT-985

(R) -MLT-985 is a potent and selective MALT1 protease inhibitor with an IC50 of 3 nM. It effectively blocks MALT1-dependent IL-2 production in Jurkat cells (IC50: 20 nM) and suppresses pathogenic CARD11/BCL10/MALT1 signaling and growth in ABC-DLBCL cell models, making it a valuable research tool for studying lymphomas and immune signaling pathways.

Product Specifications

CAS Number

1832577-07-7

Field of Research

Immunology & Inflammation

Smiles

[C@@H] (OC) (C) C=1N2C (N=CC1NC (NC=3C=C (Cl) C (=NC3) N4N=CC=N4) =O) =CC (Cl) =N2

Molecular Formula

C17H15Cl2N9O2

Molecular Weight

448.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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