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XEN907

XEN907 is a novel spiro oxindole compound that potently blocks the NaV1.7 voltage-gated sodium channel, exhibiting an IC50 of 3 nM against the human isoform (hNaV1.7) . This selective inhibitor is a valuable research tool for investigating pain pathways in both in vitro electrophysiology studies and in vivo preclinical models of nociception.

Product Specifications

CAS Number

912656-34-9

Product Name Alternative

XEN 907, XEN907, XEN-907

Field of Research

Pharmacology & Drug Discovery

Purity

99.26% (May vary between batches)

Solubility

DMSO:60 mg/mL (170.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.69 mM)

Smiles

CCCCCN1C (=O) C2 (COc3cc4OCOc4cc23) c2ccccc12

Molecular Formula

C21H21NO4

Molecular Weight

351.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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