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HDAC-IN-34

Product Specifications

Target

MDM-2/p53, Others, Apoptosis, HDAC

Related Pathways

Chromatin/Epigenetic, Others, Apoptosis, DNA Damage/DNA Repair

Bioactivity

HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC, targeting HDAC1 (IC50: 0.022 μM) and HDAC6 (IC50: 0.45 μM) . It can bind to DNA and induce DNA damage, exhibiting a significant anti-proliferative effect on HCT-116 cells (IC50: 1.41 μM) .

Molecular Formula

C24H26N6O3

Molecular Weight

446.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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