SB-525334
SB-525334 is a potent and selective inhibitor targeting the TGF-β type I receptor ALK5, with an IC50 of 14.3 nM. It is widely used in research to investigate TGF-β signaling pathways in fibrosis, cancer, and cardiovascular disease, both in cellular assays and animal models.
Product Specifications
CAS Number
356559-20-1
Product Name Alternative
ALK4, ALK5, Inhibitor, inhibit, TβR1I, Transforming growth factor beta receptors, TGFb, TGF-b/Smad, TGFbeta/Smad, TGF-beta, TGFbeta, TGF-β Receptor, TGF-β/Smad, TGFβ, Smad, SB 525334, SB525334, SB-525334
Field of Research
Immunology & Inflammation, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
ALK5 (TGF bR1) inhibitor
Form
Powder
Solubility
Soluble in DMSO (up tp 30 mg/ml)
Smiles
C (C) (C) (C) C=1NC (=C (N1) C=2N=C (C) C=CC2) C3=CC4=C (C=C3) N=CC=N4
Molecular Formula
C21H21N5
Molecular Weight
343.42
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-[2- (1,1-Dimethylethyl) -5- (6-methyl-2-pyridinyl) -1H-imidazol-4-yl]quinoxaline
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