Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

EXQ-2d

Product Specifications

Target

Wnt/beta-catenin, PARP

Related Pathways

Stem Cells, DNA Damage/DNA Repair, Cytoskeletal Signaling, Chromatin/Epigenetic

Bioactivity

EXQ-2d is an inhibitor of tankyrase, effectively targeting TNKS1 and TNKS2 with IC50 values of 48.8 nM and 13.8 nM (pIC50=7.31 and 7.86), respectively. Additionally, EXQ-2d suppresses the WNT/β-catenin signaling pathway with an IC50 of 515 nM. It demonstrates antiproliferative activity in cancer cells COLO 320DM and RKO, with GI50 values of 4.9 μM and 77 μM, respectively.

Molecular Formula

C18H17N3O3

Molecular Weight

323.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-ZNF165 Mouse Monoclonal Antibody [Clone ID: OTI4C1]
M12869 100 µL

Anti-ZNF165 Mouse Monoclonal Antibody [Clone ID: OTI4C1]

Sign In for Pricing
View Details
2,2,2-Trifluoro-1- (oxolan-3-yl) ethan-1-amine
SDC05679-01 50 mg

2,2,2-Trifluoro-1- (oxolan-3-yl) ethan-1-amine

Sign In for Pricing
View Details
2,2,2-Trifluoro-1- (oxolan-3-yl) ethan-1-amine
SDC05679-02 0.5 g

2,2,2-Trifluoro-1- (oxolan-3-yl) ethan-1-amine

Sign In for Pricing
View Details
TFEB (Transcription Factor EB, AlphaTFEB, TCFEB, bHLHe35) (MaxLight 405) discontinued
252570-ML405 100 µL

TFEB (Transcription Factor EB, AlphaTFEB, TCFEB, bHLHe35) (MaxLight 405) discontinued

Sign In for Pricing
View Details
SERINC2 Protein Vector (Rat) (pPM-C-HA)
PV304212 500 ng

SERINC2 Protein Vector (Rat) (pPM-C-HA)

Sign In for Pricing
View Details
Compound Fr13685
Fr13685-01 100 mg

Compound Fr13685

Sign In for Pricing
View Details