Mevastatin
Mevastatin (ML236B), the first statin clinically trialed, is a fungal-derived HMG-CoA reductase inhibitor. It serves as a foundational research tool for studying cholesterol biosynthesis and has been utilized in both in vitro enzymatic assays and in vivo models of hyperlipidemia.
Product Specifications
CAS Number
73573-88-3
Product Name Alternative
ENOS, EGFR, Inhibitor, HMG-CoA reductase, HMG-CoA Reductase (HMGCR), HMGCoA Reductase, HMGCR, HMGCoAReductase, NF-κB, neuroprotection, ML236B, Mevastatin, lipid-lowering, inhibit, BMP-2, cardiovascular, Autophagy, Bacterial, Antibiotic, Apoptosis, CES1, Compactin, Statins, phosphorylation, RANKL
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research
Purity
97.96% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:83.33 mg/mL (213.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.12 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C (C[C@@H]1C[C@@H] (O) CC (=O) O1) [C@@H]2[C@]3 ([C@@H] (OC ([C@H] (CC) C) =O) CCC=C3C=C[C@@H]2C) [H]
Molecular Formula
C23H34O5
Molecular Weight
390.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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