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Benfotiamine

Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways (the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG) protein kinase C (PKC) pathway) of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.

Product Specifications

CAS Number

22457-89-2

Product Name Alternative

Benzoylthiamine monophosphate

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Soluble in DMSO

Smiles

O=C (S/C (CCOP (O) (O) =O) =C (N (CC1=CN=C (C) N=C1N) C=O) /C) C2=CC=CC=C2

Molecular Formula

C19H23N4O6PS

Molecular Weight

466.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(Z) -S- (2- (N- ((4-amino-2-methylpyrimidin-5-yl) methyl) formamido) -5- (phosphonooxy) pent-2-en-3-yl) benzothioate

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