Benfotiamine
Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways (the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG) protein kinase C (PKC) pathway) of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
Product Specifications
CAS Number
22457-89-2
Product Name Alternative
Benzoylthiamine monophosphate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
O=C (S/C (CCOP (O) (O) =O) =C (N (CC1=CN=C (C) N=C1N) C=O) /C) C2=CC=CC=C2
Molecular Formula
C19H23N4O6PS
Molecular Weight
466.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(Z) -S- (2- (N- ((4-amino-2-methylpyrimidin-5-yl) methyl) formamido) -5- (phosphonooxy) pent-2-en-3-yl) benzothioate
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