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Lenalidomide

Lenalidomide is an orally active immunomodulatory agent that functions as a cereblon (CRBN) ligand. It induces the CRBN-CRL4 E3 ubiquitin ligase to selectively target and degrade the transcription factors IKZF1 and IKZF3. This mechanism underpins its research applications in hematology, immunology, and as a foundational component in PROTAC development for targeted protein degradation studies.

Product Specifications

CAS Number

191732-72-6

Product Name Alternative

CC-5013

Field of Research

Cardiovascular Research, Immunology & Inflammation

Purity

>98%

Bioactivity

TNFa inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 30 mg/ml) .

Smiles

NC1=C2CN (C3CCC (=O) NC3=O) C (=O) C2=CC=C1

Molecular Formula

C13H13N3O3

Molecular Weight

259.26

Storage Conditions

RT

Notes

For research use only.

Other Product Names

(R, S) -3- (4-Amino-1-oxo-3H-isoindol-2-yl) piperidine-2,6-dione

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