Velpatasvir
Velpatasvir (GS-5816) is a pan-genotypic HCV NS5A inhibitor with a high barrier to resistance. It is widely used in antiviral research, demonstrating potent activity in both in vitro replicon assays and in clinical studies for genotypes 1-6, and is a key component of combination therapies.
Product Specifications
CAS Number
1377049-84-7
Product Name Alternative
GS-5816
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
>98%
Bioactivity
Hepatitis C protease inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
COC[C@H]1C[C@H] (N (C1) C (=O) [C@H] (NC (=O) OC) c1ccccc1) c1ncc ([nH]1) -c1ccc-2c (COc3cc4c5[nH]c (nc5ccc4cc-23) [C@@H]2CC[C@H] (C) N2C (=O) [C@@H] (NC (=O) OC) C (C) C) c1
Molecular Formula
C49H54N8O8
Molecular Weight
883.0
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Methyl [ (2S) -1-[ (2S,5S) -2-[9-[2-[ (2S,4S) -1-[ (2R) -2-[ (methoxycarbonyl) amino]-2-phenylacetyl]-4- (methoxymethyl) pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
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