(Rac) -SAR131675
SAR131675 is a highly specific VEGFR-3 tyrosine kinase inhibitor with in vitro IC50 values of 20 nM and 45 nM for kinase activity and autophosphorylation, respectively. Its in vivo antitumor and antimetastatic effects are mediated through the inhibition of lymphangiogenesis and tumor-associated macrophage invasion.
Product Specifications
CAS Number
1092539-44-0
Product Name Alternative
Inhibitor, inhibit, (Rac) SAR131675, (Rac) SAR131675, (Rac) -SAR131675, (Rac) -SAR-131675, SAR131675, SAR-131675, SAR 131675, selective, potent, racemate, Vascular endothelial growth factor receptor, VEGFR3, VEGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.34% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
CCn1c (N) c (C (=O) NC) c (=O) c2ccc (nc12) C#C[C@@] (C) (O) COC
Molecular Formula
C18H22N4O4
Molecular Weight
358.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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