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Theophylline

Theophylline (1,3-Dimethylxanthine) is a natural methylxanthine found in tea that acts as a non-selective phosphodiesterase inhibitor, elevating intracellular cAMP levels. This mechanism underpins its research applications in studying bronchial relaxation, cardiac stimulation, and inflammatory pathways in both cellular and animal models.

Product Specifications

CAS Number

58-55-9

Product Name Alternative

Chronic obstructive pulmonary disease, Endogenous Metabolite, Autophagy, asthma, 1,3-Dimethylxanthine, airway smooth muscle, Adenosine Receptor, Adenosine receptor, AdenosineReceptor, A549 cells, HDAC2, Inhibitor, EndogenousMetabolite, eosinophils, PDE, NF-κB, inhibit, I-κBα, P1 receptor, Theophylline, Theo 24, Theo24, Theo-24, Phosphodiesterase (PDE), phosphodiesterase

Field of Research

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

99.47% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.55 mM) ; DMSO:16.83 mg/mL (93.42 mM)

Smiles

CN1C2=C (NC=N2) C (=O) N (C) C1=O

Molecular Formula

C7H8N4O2

Molecular Weight

180.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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