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Fumagillin

Fumagillin (Amebacilin) is an irreversible and selective inhibitor of Methionine Aminopeptidase 2 (MetAP2) . It is employed as an antibiotic against microsporidiosis and serves as a key research tool in studying angiogenesis, tumor growth, and obesity in both in vitro and in vivo models.

Product Specifications

CAS Number

23110-15-8

Product Name Alternative

Antibiotic, Amebacilin, NSC 9168, inhibit, NSC9168, NSC-9168, Parasite, MetAP2, Inhibitor, HIV, HIV Protease, HIVProtease, Human immunodeficiency virus, Fumagillin

Field of Research

Cardiovascular Research

Purity

>98%

Bioactivity

MetAP-2 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) .

Smiles

[H][C@@]1 ([C@H] (OC) [C@@H] (CC[C@]11CO1) OC (=O) \C=C\C=C\C=C\C=C\C (O) =O) [C@@]1 (C) O[C@@H]1CC=C (C) C

Molecular Formula

C26H34O7

Molecular Weight

458.54

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(2E,4E,6E,8E) -Mono[ (3R,4S,5S,6R) -5-methoxy-4-[ (2R,3R) -2-methyl-3- (3-methyl-2-butenyl) oxiranyl]-1- oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester

Available Sizes

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