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VX-150

VX-150 is a potent and selective small molecule inhibitor of the NaV1.8 sodium channel, demonstrating over 400-fold selectivity against other subtypes. This selectivity makes it a valuable research tool for investigating NaV1.8's role in pain signaling, both in cellular assays and in vivo models of neuropathic and inflammatory pain.

Product Specifications

CAS Number

1793080-72-4

Product Name Alternative

Inhibitor, orally, Na+ channels, Na channels, Nav1.8 channel, indications, inhibit, pain, SodiumChannel, Sodium Channel, VX 150, VX150, VX-150

Field of Research

Pharmacology & Drug Discovery

Purity

95.06% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.75 mM) ; DMSO:125 mg/mL (242.09 mM)

Smiles

O (C1=C (C (NC2=CC (=O) N (COP (=O) (O) O) C=C2) =O) C=CC (C (F) (F) F) =C1) C3=C (C) C=C (F) C=C3

Molecular Formula

C21H17F4N2O7P

Molecular Weight

516.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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