FGFR-IN-11

FGFR-IN-11 is a potent, orally bioavailable covalent inhibitor of FGFR1-4, with IC50 values ranging from 1.8 to 16 nM. It demonstrates robust anti-proliferative activity in cancer cell lines and effectively suppresses tumor growth in mouse xenograft models, supporting its use in oncology research for targeting FGFR-driven cancers.