Atosiban
A nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist; inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane; is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Other Indication Approved.
Product Specifications
CAS Number
90779-69-4
Product Name Alternative
RW-22164, RWJ-22164
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: <10.3 mg/mL
Smiles
CCOc1ccc (C[C@H]2NC (CCSSC[C@@H] (C (N3CCC[C@H]3C (N[C@H] (C (NCC (N) =O) =O) CCCN) =O) =O) NC ([C@@H] (NC ([C@H] ([C@H] (O) C) NC ([C@H] ([C@H] (CC) C) NC2=O) =O) =O) CC (N) =O) =O) =O) cc1
Molecular Formula
C43H67N11O12S2
Molecular Weight
994.1886
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Glycinamide, O-ethyl-N- (3-mercapto-1-oxopropyl) -D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1→5) -disulfide
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