IQ-1
A small molecule, specific inhibitor of p300/β-catenin interaction that binds to PR72/130 subunit of PP2A; decreases phosphorylation of p300 at Ser-89 and disrupts β-catenin/p300 interaction, prevents β-catenin coactivator switching from CBP to p300, maintains the pluripotency of murine ESCs in long-term culture in a Wnt-dependent manner.
Product Specifications
CAS Number
331001-62-8
Product Name Alternative
IQ 1 | IQ1
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 33 mg/mL
Smiles
CC (=O) C1=CC=C (C=C1) NN=C (C2=NC (CC3=CC=CC=C32) (C) C) C (=O) N
Molecular Formula
C21H22N4O2
Molecular Weight
362.42498
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Acetamide, 2-[2- (4-acetylphenyl) diazenyl]-2- (3,4-dihydro-3,3-dimethyl-1 (2H) -isoquinolinylidene)
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