SGI-7079
SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance.
Product Specifications
CAS Number
1239875-86-5
Product Name Alternative
SGI-7079 | SGI 7079 | SGI7079
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 34 mg/mL. 74.64 mM
Smiles
CN1CCN (CC1) c1ccc (Nc2nc3c (c (C) c[nH]3) c (n2) c2cc (CC#N) ccc2) cc1F
Molecular Formula
C26H26FN7
Molecular Weight
455.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (3- (2- ((3-fluoro-4- (4-methylpiperazin-1-yl) phenyl) amino) -5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) phenyl) acetonitrile
Available Sizes
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