HSR-IN-1
Product Specifications
UNSPSC Description
HSR-IN-1 (Compound 28) is an effective hSR (human serine racemase) inhibitor. In the presence of the cofactor Pyridoxal 5'-phosphate monohydrate (HY-W011727A), HSR-IN-1 has a Kd value of 5.4 μM and an IC50 of 18.3 μM for hSR, while the IC50 of HSR-IN-1 alone is 4.7 μM. HSR-IN-1 can be used for research on central nervous system diseases[1].
Target Antigen
SR
Type
Reference compound
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hsr-in-1.html
Smiles
[NH3+]OC(C(O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1.[Cl-]
Molecular Weight
293.75
References & Citations
[1]Marchesani F, et al. Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162652/HSR-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162652/
Clinical Information
No Development Reported
Curated Selection
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