Eicosapentaenoyl serotonin
Eicosapentaenoyl serotonin (EPA-5-HT) is an N-acyl serotonin, a novel lipid present in the gut. Eicosapentaenoyl serotonin inhibits glucagon-like peptide-1 secretion and FAAH activity[1].
Product Specifications
CAS Number
[199875-71-3]
Product Name Alternative
EPA-5-HT
UNSPSC
12352005
Hazard Statement
H225, H319
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/eicosapentaenoyl-serotonin.html
Concentration
21.71 mM * 100 μL in Ethanol
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)NCCC1=CNC2=CC=C(C=C12)O
Molecular Formula
C30H40N2O2
Molecular Weight
460.65
Precautions
H225, H319
References & Citations
[1]Verhoeckx KC, et al. Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract. Biochim Biophys Acta. 2011 Oct;1811 (10) :578-86.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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