Custirsen
Custirsen is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.
Product Specifications
CAS Number
890056-27-6
Product Name Alternative
OGX-011
UNSPSC
12352208
Target
Apoptosis
Type
Oligonucleotides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/custirsen.html
Purity
96.12
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
[Custirsen]
Molecular Formula
C231H312N78O119P20S20
Molecular Weight
7346.00
References & Citations
[1]Chi KN, Eisenhauer E, Fazli L, et al. A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst. 2005;97 (17) :1287-1296.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRV-0030681 96 Tests
Multiplex Assay Kit for Folate Receptor 1, Adult (FOLR1), etc. by FLIA (Flow Luminescence Immunoassay)
Sign In for Pricing
View Details 
orb1582120 100 µL
Phospho-HSP70 (Tyr41) Rabbit Polyclonal Antibody (APC-Cy7)
Sign In for Pricing
View Details 
K0210704 1.0 µg DNA
C1orf109 sgRNA CRISPR Lentivector (Human) (Target 3)
Sign In for Pricing
View Details VD12N536 1 Each
Mouse Anti-Canine Actin Cytoplasmic 1 (Actin β) Monoclonal Antibody-[HRP]
Sign In for Pricing
View Details 