Agitoxin-2

This compound is a potent and selective blocker of Shaker-type potassium channels, exhibiting sub-nanomolar affinity (Ki = 0.64 nM) . It also potently inhibits Kv1.3, Kv1.6, and Kv1.1 channels. It is a valuable research tool for electrophysiology and for studying potassium channel function in autoimmune, neurological, and cardiovascular research contexts.