(1-Nitroethene-1,2-diyl) dibenzene
(1-Nitroethene-1,2-diyl) dibenzene (alpha-Nitrostilbene; α-Nitrostilbene) is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50=11 μM in histone H4 methylation assay) . It also inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, at concentrations of 10 and 100 μM.
Product Specifications
CAS Number
[1215-07-2]
Product Name Alternative
Alpha-Nitrostilbene; α-Nitrostilbene; NSC 385
UNSPSC
12352005
Hazard Statement
H302
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-nitroethene-1-2-diyl-dibenzene.html
Smiles
O=[N+](/C(C1=CC=CC=C1)=C/C2=CC=CC=C2)[O-]
Molecular Formula
C14H11NO2
Molecular Weight
225.24
Precautions
P264-P270-P330-P501
References & Citations
[1]Dillon, et al. Novel inhibitors for PRMT1 discovered by high-throughput screening using activity-based fluorescence polarization. ACS Chem. Biol. 7 (7), 1198-1204 (2012) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6392192-01 0.1 mL
RBP4 (Retinol-binding Protein 4, Plasma Retinol-binding Protein, PRBP, RBP, PRO2222) (HRP)
Sign In for Pricing
View Details 
MBS6392192-02 5x 0.1 mL
RBP4 (Retinol-binding Protein 4, Plasma Retinol-binding Protein, PRBP, RBP, PRO2222) (HRP)
Sign In for Pricing
View Details 
MBS6335818-01 0.2 mL
POLR3GL, ID (POLR3GL, DNA-directed RNA polymerase III subunit RPC7-like, DNA-directed RNA polymerase III subunit G-like) (AP)
Sign In for Pricing
View Details MBS6335818-02 5x 0.2 mL
POLR3GL, ID (POLR3GL, DNA-directed RNA polymerase III subunit RPC7-like, DNA-directed RNA polymerase III subunit G-like) (AP)
Sign In for Pricing
View Details 
LV721144 1.0 µg DNA
CHL1-AS1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details