C10orf2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Abbreviation
C10orf2
UniProt
Q96RR1
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide of human C10orf2 (NP_068602.2) .
Target
TWNK; ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling; Neuroscience
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/mpdyy5
Product MSDS
https://789.bio/eb/0GKmP4
Calculated Molecular Weight
60kDa/66kDa/77kDa
Observed Molecular Weight
77kDa
Isotype
IgG
Available Sizes
Curated Selection
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