Phospho-JAK3 (Tyr785) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .
Abbreviation
JAK3 (phospho Tyr785)
UniProt
P52333
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785
Target
EC 2.7.10.2; JAK 3; JAK L; JAK-3; Jak3; JAK3 HUMAN; JAK3; JAKL; Janus kinase 3 (a protein tyrosine kinase; leukocyte) ; Janus kinase 3; Janus Kinase3; L JAK; L-JAK; Leukocyte janus kinase; LJAK; Protein tyrosine kinase leukocyte; Tyrosine protein kinase JAK3; Tyrosine-protein kinase JAK3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
125kDa
Observed Molecular Weight
125kDa
Isotype
IgG
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
KLR1963 96 Well
Rat Fibroblast Growth Factor Receptor 4, FGFR4 GENLISA ELISA
Sign In for Pricing
View Details bs-7451R-PE-Cy7 100 µL
Histone H3 (acetyl K27) Polyclonal Antibody, PE-Cy7 Conjugated
Sign In for Pricing
View Details 
RM-E131813-01 10 mg
Empagliflozin Impurity 213 (Ertugliflozin Diastereomer)
Sign In for Pricing
View Details RM-E131813-02 25 mg
Empagliflozin Impurity 213 (Ertugliflozin Diastereomer)
Sign In for Pricing
View Details