Scopoletin
Scopoletin is an inhibitor of acetylcholinesterase (AChE) .
Product Specifications
CAS Number
[92-61-5]
Product Name Alternative
Gelseminic acid; Chrysatropic acid
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Apoptosis; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Scopoletin.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CC(OC)=C(O)C=C2O1
Molecular Formula
C10H8O4
Molecular Weight
192.17
Precautions
H302
References & Citations
[1]Hornick A, et al. The coumarin Scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory. Neuroscience. 2011 Dec 1;197:280-92.|[2]Liu XL, et al. Effect of Scopoletin on PC3 cell proliferation and apoptosis. Acta Pharmacol Sin. 2001 Oct;22 (10) :929-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Curated Selection
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