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CD249 rabbit pAb

Catalytic activity: Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide. Cofactor: Binds 1 zinc ion per subunit. function: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. similarity: Belongs to the peptidase M1 family. subunit: Homodimer; disulfide-linked. tissue specificity: Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.

Product Specifications

Background

Catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide., cofactor:Binds 1 zinc ion per subunit., function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells., similarity:Belongs to the peptidase M1 family., subunit:Homodimer; disulfide-linked., tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.

UniProt

Q07075

Swiss Prot

Q07075

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human ENPEP. AA range:671-720

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

110kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

110kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type II membrane protein.

Other Product Names

ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249

Gene ID (Human)

2028

Available Sizes

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