CD249 rabbit pAb
Catalytic activity: Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide. Cofactor: Binds 1 zinc ion per subunit. function: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. similarity: Belongs to the peptidase M1 family. subunit: Homodimer; disulfide-linked. tissue specificity: Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
Product Specifications
Background
Synonyms
ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249
Gene ID
2028
UniProt
Q07075
Cellular Locus
Cell membrane ; Single-pass type II membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ENPEP. AA range:671-720
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
110kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8413-1.pdf
Observed Molecular Weight
110 kD
Subcellular Location
Cell membrane ; Single-pass type II membrane protein.
Other Product Names
ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249
Gene ID (Human)
2028
SwissProt (Human)
Q07075
Available Sizes
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