EZN-2968
EZN-2968 is an antisense oligonucleotide that specifically binds and inhibits the expression of HIF-1α mRNA. EZN-2968, inhibits tumor cell growth.
Product Specifications
CAS Number
[1098309-50-2]
Product Name Alternative
RO 707179
UNSPSC
12352208
Target
HIF/HIF Prolyl-Hydroxylase
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezn-2968.html
Solubility
10 mM in H2O
Smiles
[EZN-2968]
References & Citations
[1]Greenberger LM, Horak ID, Filpula D, et al. A RNA antagonist of hypoxia-inducible factor-1alpha, EZN-2968, inhibits tumor cell growth. Mol Cancer Ther. 2008;7 (11) :3598-3608. doi:10.1158/1535-7163.MCT-08-0510
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 1
Curated Selection
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