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Anti-QPCT Antibody

Boster Bio Anti-QPCT Antibody catalog # A06517. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glutaminyl-peptide cyclotransferase;2.3.2.5; Glutaminyl cyclase; QC; sQC; Glutaminyl-tRNA cyclotransferase; Glutamyl cyclase; EC; QPCT;

Gene Name

QPCT

UniProt

Q16769

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human QPCT.

Clonality

Polyclonal

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Molecular Weight

40877 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Glutaminyl-peptide cyclotransferase

Subcellular Location

Secreted

Protein Name

Glutaminyl-peptide cyclotransferase

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