Recombinant Human MOG Protein (E.coli, His Tag)
Product Specifications
Background
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE) ; in rodents and monkeys.
Abbreviation
MOG
Synonyms
BTN6; BTNL11; MOG; MOGIG2; Myelin-Oligodendrocyte Glycoprotein; NRCLP7
UniProt
Q16653
Accession Number
Q16653
Expression System
E.coli
Tag
C-His
Sequence
Gly30-Gly154
Field of Research
Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.2 kDa
Observed Molecular Weight
16-18 kDa
Species
Human
Available Sizes
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