AG01 Antibody
AG01 is a monoclonal antibody targeting the anti-granular protein precursor (GP88) . It inhibits the proliferation and migration of triple-negative breast cancer (TNBC) cells, reducing the expression of phosphorylated protein kinases such as p-Src, p-AKT, and p-ERK, as well as oncogenic proteins like Axl, c-MET, HIF-1α, and VEGF. In TNBC xenograft mouse models, AG01 suppresses tumor growth and the expression of Ki67 in vivo. AG01 is useful for research involving cancers like TNBC.
Product Specifications
Target
HIF/HIF Prolyl-Hydroxylase, Src, Akt, c-Met/HGFR, ERK, VEGFR, TAM Receptor, MMP
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Protein Biochemistry, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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