RANTES
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV) . Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Product Specifications
Synonyms
CCL5; SISd; SCYA5; RANTES; TCP228; D17S136E
NCBI Gene ID
6352
UniProt
P13501
Accession Number
NP_002976.2
Accession Number mRNA
NM_002985
Chromosomal Location
17q11.2-q12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human RANTES (CCL5)
Applications
ELISA, N, WB, IHC
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Mouse
Isotype
IgG2b
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