Ac2-26 acetate
Product Specifications
Target
NF-κB
Related Pathways
NF-κB
Bioactivity
Ac2-26 acetate is an active N-terminal peptide of annexin A1 (AnxA1) . Ac2-26 acetate decreases AnxA1 protein expression and inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue. Ac2-26 acetate attenuates ischemia-reperfusion-induced acute lung injury.
Smiles
CC[C@H](C)[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](Cc(cc1)ccc1O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](Cc1ccccc1)NC([C@H](Cc1c[nH]c2c1cccc2)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](Cc1ccccc1)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CCSC)NC([C@H](C)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C141H210N32O44S
Molecular Weight
3089.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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